SOP Title: Poisonous Chemicals
- Objective:
To lay down the procedure for Handling of Poisonous Chemicals used in Quality Control Department.
- Scope:
This procedure is applicable for control, careful handling and issue of Poisonous Chemicals used in the Quality Control Department.
- Responsibility:
- Quality Control Department: To prepare and review the SOP. To follow the procedure for control and careful handling and issue of Poisonous Chemicals as per this SOP.
- Quality Assurance Department: To review and approve the SOP and Annexure.
- Accountability:
Head Quality Control Department, Head Quality Assurance Department
- Procedure:
| 5.1 | Safety precautions: | |
| 5.1.1 | Use personal protective equipment such as hand gloves, nose masks, goggles while working with hazardous, corrosive, flammable, toxic chemicals. | |
| 5.1.2 | Strictly follow the precautions, warning mentioned on chemical/reagent bottles or refer Material Safety Data Sheets (MSDS) which provide information concerning the safe handling of chemicals, their storage, hazards, first aid and disposal. | |
| 5.1.3 | Do not store or expose the chemicals near the flame or excessive heat. | |
| 5.1.4 | Do not draw any liquid into pipette by mouth as the chemical/solvent in the pipette may enter into the mouth. Use rubber bulb or other pipetting aids. | |
| 5.2 | Procedure for Handling of Poisonous Chemicals: | |
| 5.2.1 | For receipt of Poisonous Chemicals refer SOP ‘Receipt, Storage and Handling of Chemicals in Laboratory’. | |
| 5.2.2 | Enter the details of the Poisonous Chemicals received in “Chemical Receipt Register” and affix receipt label as per SOP. | |
| 5.2.3 | Refer Annexure for list of Poisonous Chemicals. | |
| 5.2.4 | Maintain the “Poisonous Chemical Stock and Consumption Record” as per define Annexure. | |
| 5.2.5 | Preparation procedure shall be carried out in a well-ventilation fuming hood. | |
| 5.2.6 | Store Poisonous Chemicals in separate cupboard with lock and key under supervisor control. | |
| 5.2.7 | The key should be with Supervisor /Head of Department. | |
| 5.2.8 | Affix dangerous mark sticker indicating they are poisonous chemicals. | |
| 5.2.9 | Whenever any new Poisonous Chemical is taken from the stock for use, analyst should enter the date of opening on receipt label and entry should be made on “Poisonous Chemical Stock and Consumption Record” as per Annexure. | |
| 5.2.10 | In-case of accidental spillage of any acid on hands or face or clothing, wash with plenty of water at the eyewash and shower station. If irritation occurs seek medical advice. | |
| 5.2.11 | In-case of inhalation of Poisonous Chemicals, give Antidotes as per define Annexure. | |
| 5.2.12 | If the expiry date of Poisonous Chemicals/Solvents is not defined by the manufacturer then all the Poisonous Chemicals/Solvents should be used within three years after the date of opening. | |
| 5.2.13 | Example: If the analyst opens Arsenic bottle on 25/06/24, then the date of opening shall be 25/06/24 and the validity shall be 24/06/27. | |
| 5.2.14 | If the expiry date of Poisonous Chemicals/Solvents is defined by the manufacturer earlier than three years from the date of opening then assign validity same as manufacturer’s expiry date. | |
| 5.2.15 | Example: If Formaldehyde bottle has expiry date as 05/2024 and the analyst opens Formaldehyde bottle on 18/06/22, then the date of opening shall be 18/06/22 and the validity shall be 31/05/24. | |
| 5.2.16 | Consider the last date of expiry month to assign validity. | |
| 5.2.17 | Intact poisonous chemicals/solvents should be used within five years from the date of manufacturing. | |
| 5.2.18 | If the date of manufacturing is not available then intact poisonous chemicals/solvents should be used within five years from the date of receipt. | |
| 5.2.19 | If any poisonous chemicals/solvents shows deterioration e.g. sedimentation, precipitation, crystallisation, discoloration, change in physical appearance shall be discarded regardless of validity. | |
| 5.2.20 | For destruction of any Poisonous Chemicals/Solvents, refer SOP “Destruction of Laboratory Waste”. | |
Definitions / Abbreviations:
- Definitions:
- Abbreviations:
| Abbreviation | Expansion |
| SOP | Standard Operating Procedure |
| QC | Quality Control |
| QA | Quality Assurance |
| MSDS | Material Safety Data Sheet |
*Note – Ready to use SOP available in “DOWNLOAD” Section.