{"id":781,"date":"2025-06-14T13:52:05","date_gmt":"2025-06-14T13:52:05","guid":{"rendered":"https:\/\/pharmacoguide.com\/?p=781"},"modified":"2025-06-14T13:52:05","modified_gmt":"2025-06-14T13:52:05","slug":"sop-title-operation-cleaning-and-calibration-of-water-bath","status":"publish","type":"post","link":"https:\/\/pharmacoguide.com\/?p=781","title":{"rendered":"SOP Title: Operation, Cleaning and Calibration of Water Bath"},"content":{"rendered":"

SOP Title:<\/u><\/strong> Operation, Cleaning and Calibration of Water Bath<\/u><\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

    \n
  1. Objective:<\/strong><\/li>\n<\/ol>\n

    To lay down the procedure for Operation, Cleaning and Calibration of Water Bath.<\/p>\n

     <\/p>\n

      \n
    1. Scope:<\/strong><\/li>\n<\/ol>\n

      This SOP is applicable for Operation, Cleaning and Calibration of Water Bath located in Quality Control Laboratory.<\/p>\n

        \n
      1. Responsibility:<\/strong><\/li>\n<\/ol>\n
          \n
        • Quality Control: To prepare and review the SOP. To follow the procedures laid down for operation, cleaning and calibration of Water Bath as per this SOP.<\/li>\n
        • Engineering Department: To carry out preventive maintenance as per schedule and procedure defined.<\/li>\n
        • Quality Assurance Department: To review and approve the SOP and Annexures.<\/li>\n<\/ul>\n

          \u00a0<\/strong>\u00a0<\/strong><\/p>\n

            \n
          1. Accountability:<\/strong><\/li>\n<\/ol>\n

            Head Quality Control Department, Head Quality Assurance Department<\/p>\n

              \n
            1. Procedure:<\/strong><\/li>\n<\/ol>\n

              \u00a0<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
              \u00a0\u00a0\u00a0 5.1<\/strong><\/td>\nSafety Precautions\/Instructions:<\/strong><\/td>\n<\/tr>\n
              5.1.1<\/td>\nEnsure all the electrical connections are properly earthed. Ensure the power plug of the water bath is fixed in the socket properly.<\/td>\n <\/td>\n<\/tr>\n
              5.1.2<\/td>\nWear personal protective equipments such as safety glasses, hand gloves during operation of instrument.<\/td>\n <\/td>\n<\/tr>\n
              5.1.3<\/td>\nEnsure that the ON\/OFF switch is working properly by switching \u201cON\u201d the water bath.\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/strong><\/td>\n <\/td>\n<\/tr>\n
              5.2<\/strong><\/td>\nOperation:<\/strong><\/td>\n<\/tr>\n
              5.2.1<\/td>\nCheck the validity of calibration before starting any operations.<\/td>\n\u00a0<\/strong><\/td>\n<\/tr>\n
              5.2.2<\/td>\nEnsure that the equipment should be cleaned before operation.<\/td>\n <\/td>\n<\/tr>\n
              5.2.3<\/td>\nFill the water bath with sufficient purified water (i.e.\u00a0 2\/3 of its capacity).<\/td>\n <\/td>\n<\/tr>\n
              5.2.4<\/td>\nSwitch ON the ON\/OFF knob provided on the water bath.<\/td>\n\u00a0<\/strong><\/td>\n<\/tr>\n
              5.2.5<\/td>\nClose all the rings which will facilitate the boiling faster.<\/td>\n <\/td>\n<\/tr>\n
              5.2.6<\/td>\nThe\u00a0 lid\u00a0 has\u00a0 got\u00a0 six\u00a0 holes\u00a0 which\u00a0 can \u00a0be\u00a0 closed\u00a0 and\u00a0 opened\u00a0 by\u00a0 means\u00a0 of\u00a0 ring.<\/td>\n <\/td>\n<\/tr>\n
              5.2.7<\/td>\nMaintain the required temperature of the water bath with the help of temperature knob provided on the water bath.<\/td>\n <\/td>\n<\/tr>\n
              5.2.8<\/td>\nRed light on the \u201cThermostat indicator\u201d and \u201cLine indicator\u201d will glow when the required temperature is reached.<\/td>\n <\/td>\n<\/tr>\n
              5.2.9<\/td>\nEnsure that the heater of the bath is immersed below the water level.<\/td>\n <\/td>\n<\/tr>\n
              5.2.10<\/td>\nOpen the rings and place the sample on the water bath for heating.<\/td>\n <\/td>\n<\/tr>\n
              5.2.11<\/td>\nRefill the purified water in the water bath if the water level is decreased.<\/td>\n <\/td>\n<\/tr>\n
              5.2.12<\/td>\nUse only purified water to refill water bath.<\/td>\n <\/td>\n<\/tr>\n
              5.2.13<\/td>\nSwitch OFF the mains of the instrument after heating is over.<\/td>\n <\/td>\n<\/tr>\n
              \u00a0\u00a0\u00a0 5.3<\/strong><\/td>\nCleaning Procedure:<\/strong><\/td>\n<\/tr>\n
              5.3.1<\/td>\nDrain the purified water and clean the water bath thrice in a week.<\/td>\n <\/td>\n<\/tr>\n
              \u00a0\u00a0\u00a0 5.4<\/strong><\/td>\nCalibration Procedure:<\/strong><\/td>\n<\/tr>\n
              \u00a0<\/strong><\/td>\nFrequency: <\/strong>\u00a0<\/strong>Once in a year<\/td>\n<\/tr>\n
              5.4.1\u00a0 \u00a0<\/strong><\/td>\nCalibration is carried out by external agency as per SOP<\/td>\n\u00a0<\/strong><\/td>\n<\/tr>\n
              5.4.2<\/td>\nRefer Annexure for calibration test to be performed and acceptance criteria.<\/p>\n\n\n\n\n\n\n\n\n
              Sr. No.<\/strong><\/td>\nTests<\/strong><\/td>\nSet value<\/strong><\/td>\nAcceptance Criteria <\/strong><\/td>\n<\/tr>\n
              1.<\/td>\n <\/p>\n

              Temperature Verification<\/td>\n

              		50o<\/sup>C<\/td>\n\u00b15o<\/sup>C<\/td>\n<\/tr>\n
              100o<\/sup>C<\/td>\n\u00b15o<\/sup>C<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n\u00a0<\/strong><\/td>\n<\/tr>\n
              5.4.3<\/td>\nGenerate the A. R. No. on the \u201cInstrument\/Equipment Calibration Register\u201d as per SOP number and give requisition to QA department for calibration formats of instruments on the due date of calibration.<\/td>\n\u00a0<\/strong><\/td>\n<\/tr>\n
              5.4.4<\/td>\nFor issuance of calibration report refer QA SOP.<\/td>\n <\/td>\n<\/tr>\n
              5.4.5<\/td>\nIf any breakdown occurs, follow procedure as per SOP \u201cCalibration of Instruments and Equipments\u201d.<\/td>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

              \u00a0<\/strong><\/p>\n

              \u00a0<\/strong><\/p>\n

                \n
              1. Definitions \/ <\/strong>Abbreviations:<\/strong><\/li>\n<\/ol>\n
                  \n
                • Definitions:<\/strong><\/li>\n
                • Breakdown: Any activity leading to operation of instrument\/equipment other than the set parameters and\/ or unusual sound or vibration observed in the instrument\/equipment.<\/li>\n
                • Calibration: Tests performed to ensure that the instrument\/equipment is functioning as per set parameters. These tests are performed as per predefined frequency and also after any major repair or replacement of parts.<\/li>\n<\/ul>\n

                  \u00a0<\/strong>\u00a0<\/strong><\/p>\n

                    \n
                  • Abbreviations:<\/strong><\/li>\n<\/ul>\n\n\n\n\n\n\n
                    Abbreviation<\/strong><\/td>\nExpansion<\/strong><\/td>\n<\/tr>\n
                    SOP<\/td>\nStandard Operating Procedure<\/td>\n<\/tr>\n
                    QC<\/td>\nQuality Control<\/td>\n<\/tr>\n
                    QA<\/td>\nQuality Assurance<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

                    \u00a0<\/strong><\/p>\n\n\n\n\n\n
                    No.<\/td>\nNumber<\/td>\n<\/tr>\n
                    A. R. No.<\/td>\nAnalytical Reference Number<\/td>\n<\/tr>\n
                    i.e.<\/td>\nThat is<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

                    \u00a0<\/strong>\u00a0<\/strong><\/p>\n

                    *Note – Ready to use SOP available in \u201cDOWNLOAD\u201d Section.<\/u><\/em><\/strong><\/p>\n

                    \u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

                    SOP Title: Operation, Cleaning and Calibration of Water Bath \u00a0 Objective: To lay down the procedure for Operation, Cleaning and Calibration of Water Bath.   Scope: This SOP is applicable for Operation, Cleaning and Calibration of Water Bath located in Quality Control Laboratory. Responsibility: Quality Control: To prepare and review the SOP. To follow the […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"templates\/template-full-width.php","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-781","post","type-post","status-publish","format-standard","hentry","category-qc-sop"],"_links":{"self":[{"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=\/wp\/v2\/posts\/781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=781"}],"version-history":[{"count":1,"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=\/wp\/v2\/posts\/781\/revisions"}],"predecessor-version":[{"id":782,"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=\/wp\/v2\/posts\/781\/revisions\/782"}],"wp:attachment":[{"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=781"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=781"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmacoguide.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}